Clinical Studies
Study Name: Comparison of Salicylic Acid and Urea versus Ammonium Lactate for the Treatment of Foot Xerosis A Randomized, Double-Blind, Clinical Study
Author(s): Maureen B. Jennings, DPM, Donna Alfieri, DPM, Katherine Ward, DPM, Christine Lesczczynski
Journal: Study published in JAPMA, July 1998
Summary: Kerasal is clinically proven as an effective agent in the treatment of xerosis and was shown to work as well as a leading prescription product.
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Study Name: Percutaneous Absorption of Salicylic Acid in Man after Topical Administration of
Three Different Formulations
Author(s): F.P. Schwarb, B. Gabard, Th. Rufli, Ch. Surber
Journal: Study published in Dermatology, 1999
Summary: Products with the same active ingredients are not equal. Kerasal delivered more salicylic acid to the targeted organ (stratum corneum) with lower potential for excessive drug delivery to the body vs 2 other salicylic formulations.
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Study Name: In vivo measurement of the keratolytic effect of salicylic acid in three ointment formulations
Author(s): T.H. Nook
Journal: Study published in British Journal of Dermatology, 1987
Summary: The combination of 10% urea and 5% salicylic acid appears to provide synergistic pharmacological effect of the two substances vs 10% salicylic acid in petrolatum which is commonly used in the treatment of hyperkeratotic skin diseases.
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